Johanna Mrtensson1,2, Markus Nilsson2,
Christina Elfgren3, Maria Landqvist3, Freddy Sthlberg2,4,
Christer Nilsson3, Danielle van Westen1,4, Jimmy Ltt1
1Center for Medical Imaging
& Physiology, Lund University Hospital, Lund, Skane, Sweden; 2Department
of Medical Radiation Physics, Lund University Hospital, Lund, Skane, Sweden; 3Geriatric
Psychiatry, Department of Clinical Sciences, Lund University Hospital, Lund,
Skane, Sweden; 4Department of Diagnostic Radiology, Lund
University Hospital, Lund, Skane, Sweden
We present a method for spatial evaluation of MRI tractography data based on track co-registration using anatomical landmarks. The feasibility for clinical use was tested in a patient group suffering from semantic dementia. The analysis pinpointed specific areas of the track bundle where differences existed between the patient and healthy control group.