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Abstract #2081

White-Matter Tract-Based Atlas of the Chimpanzee Brain

Longchuan Li1, Susan Kramer1, William Hopkins2, Todd Preuss2, James Rilling3, Govind Nair1, Xiaodong Zhang2, Frederick Damen4, Xiaoping Hu4

1School of Medicine, Emory University, Atlanta, GA, United States; 2Division of Neuroscience, Yerkes National Primate Research Center, Atlanta, GA, United States; 3Division of Psychobiology, Yerkes National Primate Research Center, Atlanta, GA, United States; 4Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States


Although diffusion magnetic resonance imaging (MRI) and tractography have been used to generate white-matter tract based atlases of the human and macaque brain, no such atlas has been created for our closest living relative, the chimpanzee. In this study, we acquired diffusion MR data from nine chimpanzees and virtually dissected the major white-matter tracts via probabilistic tractography. We then generated an atlas of the course, location and extent of these tracts. This white-matter tract-based atlas of the chimpanzee brain will have extensive applications in comparative neurology and provide insights into primate brain evolution