Bingsheng Huang1, Pek Lan Khong1,
Chung-Sing Wong1, Dora Lai Wan Kwong2, Queenie Chan3
1The University of Hong Kong,
Hong Kong Island, Hong Kong SAR, Hong Kong; 2Clinical Oncology,
the University of Hong Kong; 3Philips Healthcare
Dynamic Contrast-enhanced MRI (DCE-MRI) is useful for estimating the tumor malignancy because the contrast enhancement pattern reflects the perfusion and permeability of the tumor as well as the tumor angiogenesis. In this study we investigated the relationship between semi-quantitative contrast enhancement parameters in dynamic DCE-MRI and the diagnosing staging of nasopharyngeal carcinoma, and the correlation between these parameters and PET-CT scanning. Our results showed that some parameters from semi-quantitative analysis of DCE-MRI significantly correlate with the T stages of NPC tumors, but not with PET-CT parameter.