Abstract #2039

Intra-Operative Perfusion Imaging of Brain Tumors using Dynamic Contrast Enhanced MRI: A Comparison with Dynamic Susceptibility Contrast MRI

Shy-Chyi Chin¹, Yeng-Peng Liao², Ya-Ting Chuang¹, Ho-Ling Liu^2,3

¹Department of Medical Imaging & Intervention, Chang-Gung Medical Center, Guei-Shan, Tao-Yuan, Taiwan; ²Chang Gung University, Department of Medical Imaging & Radiological Sciences, Guei-Shan, Tao-Yuan, Taiwan; ³Department of Medical Imaging & Intervention, Chang-Gung Medical Center

A new trend is to utilize MRI intra-operatively to assess the sufficiency of brain tumor resection, not just for better navigation. Both dynamic contrast-enhanced (DCE) and dynamic susceptibility-contrast (DSC) techniques are applied to patients after surgical resection. Our study, distinct from previous works biased toward DSC-MRI, has concluded that (1) no discrepancy between the normalized V_P from DCE-MRI and normalized CBV from DSC-MRI and (2) K^trans map from DCE-MRI seemingly more precise in denoting the permeability and extent of impaired brain-blood-barrier than K2 map from DSC-MRI.