A Novel Approach to Give More Insides on Anomalous Diffusion Processes: Diffusion MR Signal at Varying of Diffusion Time Versus Signal at Varying of Gradient Strength

Silvia Capuani^1,2, Marco Palombo¹, Silvia De Santis¹, Andrea Gabrielli³

We developed and applied a new methodology based on CTRW to investigate the type of anomalous diffusion information obtenaible using methods based on PFG signal at varying of the time and/or the gradient strenght g. using PFG experiments performed in controlled samples and human tissues with different (expected) diffusional characteristics we measured by varying and by varying g. Experimental data demonstrate that and reflect some additional microstructural information which cannot be obtained using conventional diffusion procedures based on Gaussian diffusion models. Morover, our work allows a critical revision of previous anomalous diffusion literature.