Adaptive Volumetric MR-Guided High-Intensity Focused Ultrasound Ablations

Silke Hey¹, Baudouin D. de Senneville¹, Charles Mougenot², Max Khler³, Chrit Moonen¹, Mario Ries¹

Real time feedback control of the HIFU beam position and the beam power during MR-guided interventions requires continuously updated volumetric information of the thermal dose and temperature over the entire target area. Here, a dynamic volume sweep for volumetric and motion compensated MR-thermometry and dosimetry is presented in combination with a real time adaptation of the ablation trajectory. The feedback control algorithm is based on the target temperature, as it is required for the use of HIFU in local drug delivery applications, or alternatively directly on thermal dose estimates as is preferable for the direct thermal destruction of tumors.