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Abstract #1585

Cocaine-Induced Activity in the Rat Hippocampus using PhMRI

S. K. Hekmatyar1, Madhu M. Keralapurath2, Jason Clark2, Sherri Hammond2, John J. Wagner2

1BioImaging Research Center, University of Georgia, Athens, GA, United States; 2Department of Physiology & Pharmacology, University of Georgia, Athens, GA, United States


The temporal pattern of brain activation induced by cocaine in the regions of brain (dHF and vHF) that are associated with memory and learning were studied using functional MRI techniques in three groups of urethane anesthetized (i) cocaine naive (ii) self administered and (iii) in saline injected control rats.