Delayed BOLD in the Somatosensory Cortex & Its Possible Relationship to Beta Band Event Related Synchronisation

Fan Wang¹, Claire Stevenson¹, Matthew Brookes¹, Peter Morris¹

In this work we employ a multi-model neuroimaging approach to investigate the relationship between neural oscillations and the BOLD response. We use MEG to measure the temporal profile of beta band oscillations including the characteristic event related desynchronisation (ERD) and the post stimulus synchronisation (ERS). We derive BOLD models based on the timing of ERD/ERS. Our ERS model highlights voxels with a significant delayed BOLD response. We speculate that such responses are not simply a result of haemodynamic lag, but rather that they could reflect the post stimulus beta rebound.