Effect of T1 & Flip Angle Errors on Hepatic Arterial Fraction Calculation

Daniel Wilson¹

Hepatic arterial fraction is often measured from dynamic contrast enhanced MRI data collected using a 3D spoiled gradient echo sequence. Errors in hepatic arterial fraction measurements as a consequence of flip angle and pre contrast T1 measurement errors are minimized if higher flip angles are used. The small errors found suggest that if a flip angle of 30 is prescribed then it is possible to use an assumed T1 rather than measure it.