Quentin Godechal1, Philippe Leveque1,
Liliane Marot2, Jean-Francois Baurain2, Bernard Gallez1
1Louvain Drug Research
Institute, Biomedical Magnetic Resonance Research Group, University of
Louvain, Brussels, Belgium; 2Cliniques Universitaires Saint Luc,
Brussels, Belgium
In this work, we used for the first time EPR imaging as a tool to detect and localize melanin pigments inside human melanoma. The results are very encouraging as we showed that EPR imaging might be able to provide an accurate image of samples and thus allow the determination of the Breslow index (thickness of the lesion) and Clark index (penetration of the tumor), two crucial characteristics for the diagnosis of melanoma.