Judd M. Storrs1,2, Mohan Jayatilake1,3,
Wen-Jang Chu1,2, Jing-Huei Lee1,4
1Center for Imaging Research,
University of Cincinnati, Cincinnati, OH, United States; 2Department
of Psychiatry & Behavioral Neuroscience, University of Cincinnati,
Cincinnati, OH, United States; 3Department of Physics, University
of Cincinnati, Cincinnati, OH, United States; 4School of Energy,
Environmental, Biological & Medical Engineering, University of
Cincinnati, Cincinnati, OH, United States
B0 inhomogeneity within a single-voxel MRS volume-of-interest (VOI) is measured using a 333 grid of smaller MRS voxels distributed within the VOI. A specific sequence for acqisition of the grid allows repetition time to be halved without decreasing the effective relaxation time of each grid voxel. The acquired spectra is analyzed to produce first- and second-order shim updates to improve B0 homogeneity within the VOI.