MRS Localization in the Human Brain at 7T with Adiabatic Refocusing at Short Echo Time using RF Focusing with a Dual Channel Volume Transmit Coil

Vincent Oltman Boer¹, Astrid L. H. M. W. van Lier², Johannes M. Hoogduin¹, Jannie P. Wijnen¹, Peter R. Luijten¹, Dennis W. J. Klomp¹

In vivo localization of single voxel spectroscopy at short echo time in the human brain has shown to be challenging at 7T due to the limited bandwidth of refocusing RF pulses. In this work we show that by driving a standard volume coil with two RF amplifiers, focusing the B1+ field in a certain location, and using short high bandwidth adiabatic refocusing pulses, a semi-LASER localization is feasible at short echo time with full signal acquisition and a low chemical shift displacement artifact in the human brain at 7 tesla.