Abstract #1339

Mapping of Myocardial ASL Perfusion & Perfusion Reserve Data

Terrence Jao¹, Zungho Zun², Padmini Varadarajan³, Ramdas Pai³, Krishna Nayak²

¹Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; ²Electrical Engineering, University of Southern California, Los Angeles, CA, United States; ³Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, United States

Arterial spin labeled MRI is an emerging approach for measuring myocardial perfusion and perfusion reserve in humans. The technique requires acquisition and registration of multiple tagged and control images and suffers from low signal-to-noise ratio. In this work, we address these two challenges by spatially aligning and spatio-temporally filtering myocardial ASL data in a polar coordinate frame. We demonstrate that this approach facilitates assessment of regional perfusion and perfusion reserve in patients.