Abstract #1204

Complex Flow in a Real-Size Intracranial Aneurysm Phantom: Phase Contrast MRI Compared with CFD

Pim van Ooij^1,2, Annetje Gudon^1,2, Joppe Schneiders¹, Marcel C. M. Rutten³, Henk Marquering^1,2, Charles B. Majoie¹, Ed vanBavel², Aart J. Nederveen¹

¹Radiology, Academic Medical Center, Amsterdam, Netherlands; ²Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands; ³Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

As a validation study for the use of phase contrast (PC) MRI in intracranial aneurysms high resolution time-resolved 3D PC-MRI was performed in a real-size patient-specific intracranial aneursysm phantom and compared with a CFD simulation. Qualitatively flow properties such as vortices and inflow jets were very similar. Quantitatively, small differences were found in root mean square error and velocity vector angles in voxels. This study is a first step in the application of PC-MRI in aneurysms in a clinical setting by showing that time-resolved 3D PC-MRI is capable of measuring complex flow patterns in small structures with an acceptable accuracy.