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Abstract #1162

Modeling the Hyperemic Response in Skeletal Muscle fMRI

Kiril Schewzow1,2, Martin Andreas2,3, Ewald Moser1,4, Michael Wolzt2, Albrecht Ingo Schmid1,4

1MR Center of Excellence, Medical University of Vienna, Wien, Austria; 2Dpt. of Clinical Pharmacology, Medical University of Vienna, Wien, Austria; 3Dpt. of Surgery, Medical University of Vienna, Wien, Austria; 4Centre of Medical Physics & Biomedical Engineering, Medical University of Vienna, Wien, Austria


Ischemia and reperfusion in skeletal muscle were studied by BOLD-MRI. In this work, we fitted the EPI time courses of the hyperemic response to ischemia, using similar a function as in DCE-MRI. Several parameters which describe hyperemia were determined from the fit results. Significant differences between muscle groups and the impact of post-occlusive stenosis could be shown.