Danchin Daniel Chen1, Diego Hernando2,
Curtis Laurence Johnson1, Armen Alex Gharibans1,
Dolores D. Guest3, Christie Ward4, Bhibha Das3,
Ellen M. Evans4, John G. Georgiadis1,5
1Mechanical Science &
Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United
States; 2Department of Radiology, University of Wisconsin,
Madison, WI, United States; 3Department of Kinesiology &
Community Health, University of Illinois at Urbana-Champaign, Urbana, IL,
United States; 4Department of Kinesiology, University of Georgia,
Athens, GA, United States; 5Beckman Institute for Advanced Science
& Technology, University of Illinois at Urbana-Champaign, Urbana, IL,
United States
Single-voxel 1H-MR spectroscopy was utilized in a cross-sectional study of elderly women (n=41) blocked on adiposity (obese vs. lean), with the lean group (n=17) further blocked on physical fitness (sedentary vs. physically active). The lipid distribution in the vastus medialis of lean/sedentary individuals was found to be similar to that of obese individuals, while lean/active individuals had a lower concentration of lipids (p<0.005) with a higher percentage stored as IMCL (p<0.1) than the obese and the lean/sedentary individuals.