Abstract #1064

Reproducibility of T2* MR Imaging & Correlation with Diffusion MR Imaging in Liver Metastasis of Colorectal Cancer

E. G. W. ter Voert¹, L. Heijmen², W. J. G. Oyen³, J. H. W. de Wilt⁴, C. J. A. Punt², L. F. de Geus-Oei³, H. W. M. van Laarhoven², A. Heerschap¹

¹Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; ²Medical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; ³Nuclear Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; ⁴Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

There is an increasing interest in magnetic susceptibility or T₂* MR imaging to replace or complement DCE-MRI for vascular assessment of therapeutic interventions in early treatment response monitoring, as this circumvents the need for a contrast agent. In this study we focused on the reproducibility of T₂* MR imaging in patients with liver metastases of colorectal cancer. Histogram analysis were performed and reproducibility was assessed for the mean T₂*, the 16^th and 84^th percentile values. On average T₂* showed good mean and histogram reproducibility. A trend towards a negative correlation with mean ADC values was observed.