Abstract #1051

High Resolution Ex Vivo MRI of Prostate Specimen, Correlation with Whole-Mount Histology & In Vivo MRI

Chad R. Haney¹, Xiaobing Fan¹, Garima Agrawal¹, Charles A. Pelizzari², Gregory S. Karczmar¹, Jonathan Bakst³, Tatjana Antic³, Scott E. Eggener⁴, Aytekin Oto¹

¹Radiology, University of Chicago, Chicago, IL, United States; ²Radiation & Cellular Oncology, University of Chicago, Chicago, IL, United States; ³Pathology, University of Chicago, Chicago, IL, United States; ⁴Urology/Surgery, University of Chicago, Chicago, IL, United States

Histology is the gold standard for assessing the presence or absence of cancer in prostatectomy specimen. However, the entire prostate cannot be processed and the histological processing often damages the specimen. High-resolution ex vivo MRI of the prostate can not only serve as a bridge to registering in vivo MRI with histology but can provide additional diagnostic information. We present preliminary results from 8 patients that suggests date suggest that high resolution T2-weighted ex vivo MRI differentiates between carcinoma and benign prostatic hyperplasia.