Diagnostic Performance of DCE-MR Imaging of the Breasts as a Function of Contrast Dose

Lawrence Dougherty¹, Mark Alan Rosen¹, Hee Kwon Song¹, Mitchell D. Schnall¹

The effect of gadolimium contrast dose on the diagnostic performance of DCE-MR breast imaging was studied. A population of subjects with a suspicious breast mass received a MR examination using a high dose of contrast agent independent of weight (20 ml) and a second population received a low dose (0.1 mmol/kg). The diagnostic performance, assessed using tumor morphology as well as SER, was shown to increase with the higher dose.