Jaime Mata1, Kai Ruppert1, Peter
Sylvester1, Isabel Dregely2, Talissa Altes1,
Iulian Ruset2, William Hersman2, Grady Miller1,
Steve Ketel2, Jeff Ketel2, John Mugler III1
1Radiology, University of
Virginia, Charlottesville, VA, United States; 2Xemed, LLC, Durham,
NH, United States
Using hyperpolarized Xe-129 gas and Chemical Shift Imaging, we directly calculate images reflecting the amount of Xe-129 in the airspaces, and dissolved in the lung tissue, Red Blood Cells (RBC), and other compartments, thus obtaining detailed spatial information regarding how Xe-129 is distributed in those different compartments and providing regional information about lung physiology.