Gavin Hamilton1, Michael S. Middleton1,
Takeshi Yokoo1, Lisa G. Clark1, Claude B. Sirlin1
1Department of Radiology, University
of California, San Diego, San Diego, CA, United States
We examine the repeatability of liver triglyceride characterization by 1H MR Spectroscopy using a theoretical triglyceride model. Estimates of triglyceride unsaturation obtained from 1H MRS respiratory gated and free breathing acquisitions were compared. 1H MR Spectroscopy can repeatably measure the degree of liver fat unsaturation, and spectra collected with respiratory gating give a more repeatable characterization of liver fat composition than spectra collected with free breathing.