Abstract #0847

Fully Automated Measurement of Total Adipose Tissue Volume using Quantitative Chemical Shift MRI: Phantom Validation

Aziz H. Poonawalla¹, Catherine D. G. Hines¹, Diego Hernando¹, Pablo Irarrazaval^1,2, Scott Brian Reeder¹

¹Radiology, University of Wisconsin, Madison, WI, United States; ²Biomedical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile

Fully-automated measurement of total adipose tissue using quantitative chemical shift MRI is demonstrated using a quantitative volumetric chemical-shift fat/water imaging method in phantoms. Fat, water and quantitative fat-fraction images were acquired at 3T with a 32-channel phased array in 26 sec of a series of peanut oil-filled phantoms of known volume and increasing surface area via inclusion of agar balls, glass rods, and empty vials. Robust fat volumes were measured in excellent agreement (r2 = 0.99) with known volumes of oil, with no user intervention, and immunity to partial volume effects.