Abstract #0810

Investigating the Pancreatic Function: Robust 3D MR Imaging of Mouse Abdomen

Ekkehard Kstermann¹, Anke Meyer², Amod Godbole², Wolfgang Dreher³, Kathrin Maedler²

¹ZKW, University of Bremen, Bremen, Germany; ²CBIB, University of Bremen; ³FB2, University of Bremen

Diabetes research strongly benefits from non-invasive methods of analysing pancreatic beta-cell mass. A promising strategy is to measure Manganese uptake in pancreatic tissue by T1-weighted in-vivo MR imaging. Here, a 3D ir-Snapshot-FLASH protocol for robust, least-invasive T1-weighted MR imaging of mouse abdomen in spontaneously braething mice is presented.