Abstract #0803

Evaluation of Individual Versus Average T2* Decay Correction & Single Slice Versus Multislice Sampling in the Two-Point Dixon Method for Liver Fat Quantification

Cemil Kirbas¹, Eric Zalusky¹, Stefan Czerwinski², Miryoung Lee², Ke Cheng Liu³, Jason G. Parker¹

¹Innovation Center, Kettering Health Network, Kettering, OH, United States; ²Department of Community Health, Wright State University, Kettering, OH, United States; ³Siemens Medical Solutions, United States

Assessment of fat content in the liver is of interest in the evaluation of a spectrum of diseases. Quantification of liver fat fraction using magnetic resonance imaging (MRI) has become popular recently. One of the popular MRI methods to quantify liver fat fraction is the two-point Dixon method using in-phase (IP) and out-phase (OP) images. In this study we used a Dixon-based method and evaluated the difference between using individual correction factor calculated for each subject and an average correction factor. We also evaluated the accuracy of fat fraction calculation using a ROIs from a single slice versus multiple slices.