Time-Resolved Qualitative & Quantitative Analysis of Normal & Altered 3D Portal Venous Hemodynamics in Liver Cirrhosis Patients

Zoran Stankovic¹, Zoltan Csatari¹, Peter Deibert², Wulf Euringer¹, Susanne Eggerking², Philipp Blanke¹, Zahra Abdullah Zadeh¹, Mathias Langer¹, Michael Markl¹

Flow-sensitive 4D MRI was applied for the qualitative and quantitative analysis of portal venous hemodynamics of liver cirrhosis patients (n=20) and volunteers (n=41). Our results revealed a significant correlation of 4D MRI with the reference standard Doppler Ultrasound for maximum and mean velocities and flow for the intrahepatic vessels. Quantitative flow analysis could be performed retrospectively at any location of interest and revealed significant alterations in velocities and flow in patients compare to age matched and younger control groups.