Abstract #0788

Spin- & Gradient-Echo EPI for Imaging of Brain Perfusion with MRI

Heiko Schmiedeskamp¹, Matus Straka¹, Greg Zaharchuk¹, Nancy J. Fischbein¹, Marteen G. Lansberg², Jean-Marc Olivot², Greg W. Albers², Michael E. Moseley¹, Roland Bammer¹

¹Department of Radiology, Stanford University, Stanford, CA, USA; ²Department of Neurology, Stanford University, Stanford, CA, USA

A spin- and gradient-echo (SAGE) EPI sequence was used for simultaneous acquisition of spin- and gradient-echo weighted perfusion maps through the acquisition of 5 echo trains per readout. Hereby, perfusion parameters were calculated from estimates of R2 and R2*, rather than relative changes in signal intensity, with the goal to produce T1-independent, more quantitative PWI maps and to facilitate vessel size imaging.