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Abstract #0781

Effect of Aging on CBF Mapping of Default Mode Network : An fMRI Study

Ying Hao1, Jing Liu2, Yue Zhang3, Xiaoying Wang1,4, Jue Zhang1,3, Jing Fang3,5

1Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of; 2Dept. of Radiology, Peking University First Hospital, Beijing, China, People's Republic of; 3College of Engineering, Peking University, Beijing, China, People's Republic of; 4Dept. of Radiology, Peking University First Hospital, Beijing, Beijing, China, People's Republic of; 5 Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of


This study first depicted the effect of aging on the CBF-based correlations in DMN system. Compared with adult group, the correlation of the aging group with PCC node was found significantly decreased in the areas including right vMPFC and STG, which is in accordance with the previous BOLD-based studies. In addition, this study may shed light on the potential application of CBF signals in depicting functional connectivity mapping.