Abstract #0762

Diffusion Weighted MR Imaging: Predictive Capability for Chemoradiotherapeutic Effect in Non-Small Cell Lung Cancer Patients as Compared with FDG-PET/CT

Keiko Matsumoto¹, Yoshiharu Ohno², Hisanobu Koyama², Takeshi Yoshikawa², Mizuho Nishio², Yumiko Onishi², Nobukazu Aoyama³, Daisuke Takenaka², Kazuro Sugimura²

¹Radiology, Yamanashi Hospital of Social Insurance, Kofu, Yamanashi, Japan; ²Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ³Radiology, Kobe University Hospital, Kobe, Hyogo, Japan

To the best of our knowledge, the capability of diffusion-weighted MR imaging (DWI) for prediction of therapeutic effect in advanced non-small cell carcinoma (NSCLC) patients with chemoradiotherapy as not yet been demonstrated. In the present study, we hypothesized that quantitatively assessed DWI can be utilized for prediction of therapeutic effect after chemoradiotherapy in NSCLC patients as well as FDG-PET/CT. Thus, the purpose of the present study was to directly and prospectively compare the predictive capability for therapeutic effect of chemoradiotherapy between DWI and FDG-PET/CT in NSCLC patients.