Molecular Imaging of Breast Lesions with PET-MRI: Proof of Concept

Katja Pinker¹, Stephan Gruber¹, Wolfgang Bogner¹, Siegfried Trattnig¹, Thomas H. Helbich¹

To demonstrate the feasibility of combined 3T contrast-enhanced MRI and 18FDG-PET-CT for molecular imaging of breast lesions and to assess possible increase in diagnostic sensitivity and specificity. 31 breast lesions were examined with 18FDG-PET-CT and 3T MRI of the breast, classified according to BIRADS and histopathologically verified. Sensitivity and specificity of PET-MRI was 100% and 100% respectively. Molecular imaging of breast lesions with PET-MRI is feasible. PET-MRI seems to improve diagnostic confidence in the diagnosis of breast lesions and enables accurate assessment of nodal status.