Results on Rapid 3D Magnetic Particle Imaging with a Large Field of View

Jrgen Rahmer¹, Bernhard Gleich¹, Claas Bontus¹, Ingo Schmale¹, Joachim Schmidt¹, Jrgen Kanzenbach¹, Oliver Woywode², Jrgen Weizenecker³, Jrn Borgert¹

Magnetic particle imaging (MPI) is a new tomographic imaging approach that quantitatively maps concentrations of iron oxide nanoparticle distributions. It combines high sensitivity with the ability of fast volumetric imaging. Previously, in vivo 3D real-time MPI of a bolus of particles flowing through the heart and lung of mice has been demonstrated, but with an imaging approach that is limited to small fields of view (FoVs). Recently, a new scanner type with a bore diameter of 12 cm allowing rapid imaging with enlarged FoVs has been developed. This contribution describes the sequences used for imaging of large FoVs and presents initial phantom results acquired on the new system.