MR Imaging Guided NCT by a Dual Gd/B Agent Targeted to Tumor Cells via Upregulated LDL Transporters.

Simonetta Geninatti-Crich¹, Diego Alberti¹, Ibolya Szabo¹, Antonio Toppino², Annamaria Deagostino², Paolo Venturello², Nicoletta Protti³, Silva Bortolussi³, Saverio Altieri³, Silvio Aime¹

MR guided Boron Neutron Capture Therapy (BNCT) has been performed using an imaging probe containing both Boron and Gd, targeted at tumor cells through overexpressed LDLs receptors.