Cardiac Triggering & Label-Control Transition Profiles in Hadamard Encoded Pseudo-Continuous Arterial Spin Labeling

Wouter Teeuwisse¹, Michael Helle², Susanne Rfer², Matthias J. P. van Osch¹

Hadamard encoded continuous ASL is a promising technique to obtain dynamic ASL angiography images and temporal information such as transport delay time in a short scan time. However blurring of the encoding pattern by the cardiac cycle and non instantaneous switching between label and control can hamper the efficacy. By means of simulations and in vivo experiments, the necessity of cardiac triggering is shown and a minimum switching time of 50 ms for pCASL is demonstrated.