Abstract #0214

Adenosine-Induced Stress Myocardial Perfusion MRI using SW-CG-HYPR with Whole Left Ventricular Coverage: Comparison of Results with X-Ray Angiography in Patients with Suspected Coronary Artery Disease

Heng Ma¹, Lan Ge², Jing An³, David Chen², Lixin Jin⁴, Xiaoming Bi⁵, Renate Jerecic⁴, Kuncheng Li¹, Debiao Li^2,6

¹Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of; ²Northwestern University; ³Siemens Healthcare, MR Collaboration NE Asia, Siemens Mindit Magnetic Resonance; ⁴Siemens Healthcare, MR Collaboration NE Asia, Siemens Limited China; ⁵Siemens Healthcare, Cardiovascular MR R&D, USA; ⁶Cedars-Sinai Medical Center & UCLA

Myocardial perfusion MRI with SW-CG-HYPR allows increased spatial coverage (whole left ventricular coverage), resolution, signal-to-noise ratio and reduced motion artifacts. The accuracy of this technique for detecting CAD has not been determined in a large number of patients. In this work, we have prospectively examined the diagnostic value of adenosine-induced stress myocardial perfusion MRI using SW-CG-HYPR in 50 patients with suspected CAD. Using the SW-CG-HYPR method, perfusion MRI was able to cover the whole left ventricle with an accuracy of 90% and 93% based on per-patient and per-vessel analyses, respectively, using X-ray coronary angiography as a reference standard.