Abstract #0157

Endovaginal Magnetic Resonance Imaging of Stage 1A/1B1 Cervical Cancer with a T2- & Diffusion-Weighted Magnetic Resonance Technique: Effect of Lesion Size & Previous Cone Biopsy on Tumor Detectability

Elizabeth Charles-Edwards¹, Veronica Morgan¹, Ayoma Attygalle², Sharon Giles¹, Thomas E. Ind³, Michael Davis⁴, John Shepherd³, Norman McWhinney⁵, Nandita deSouza¹

¹CRUK & EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; ²Histopathology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; ³Gynaecology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; ⁴Gynaecology, Kingston Hospital , Kingston, Surrey, United Kingdom; ⁵Gynaecology, Epsom & St. Helier NHS Trust, Epsom, Surrey, United Kingdom

Diffusion-weighted MRI using an endovaginal coil is a useful adjunct to T2-W imaging for detecting small tumours within the cervix. Following a cone biopsy/LLETZ procedure where distortion of normal tissue and granulation tissue is present, a tumor volume of 83 mm³ could be detected with 80% sensitivity, 94.7% specificity. A 5.3 mm maximal histological dimension was detected on MRI with 100% sensitivity, 100% specificity.