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Abstract #0130

Comparison of Cortical Surface Reconstructions from MP2RAGE Data at 3T & 7T

Kyoko Fujimoto1, Jonathan R. Polimeni1, Andre J. van de Kouwe1, Tobias Kober2, Thomas Benner1, Bruce Fischl1,3, Lawrence L. Wald1,4

1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA; 2Laboratory for Functional & Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Advanced Clinical Imaging Technology, Siemens Suisse SA - CIBM, Lausanne, Switzerland; 3Computer Science & AI Lab (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, USA; 4Harvard-MIT Division of Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA, USA


Here we demonstrate that accurate surface models can be generated from 7T anatomical data with the recently introduced MP2RAGE pulse sequence with some additional preprocessing steps prior to using the FreeSurfer software package. We compared the surfaces generated from 7T MP2RAGE data with those generated from 3T MP2RAGE data and 3T MEMPRAGE data. We performed a test-retest analysis with the 3T data to quantify the reproducibility of the surface models and to estimate the precision of the surface reconstruction across the two acquisition methods.