Abstract #0114

Haptoglobin Phenotype Modulates MRIPH Signal

General Leung^1,2, Helen Cheung², Stephanie E. Chiu¹, Betty Wong³, David Cole³, Alan R. Moody^1,2

¹Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; ²Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ³Division of Biochemistry & Genetics, Sunnybrook Health Sciences Centre

Intraplaque Haemorrhage (IPH) has been shown to be a predictor of patient outcome. Haptoglobin, a haemoglobin binding protein, appears to modulate the MR signal in vitro. In-vivo, haptoglobin phenotypes appears to be associated with MRIPH status.