Abstract #0053

3T MRI-Guided Transperineal Targeted Prostate Biopsy: Clinical Feasibility, Safety & Early Results

Kemal Tuncali¹, Junichi Tokuda¹, Andriy Fedorov¹, Iulian Iordachita², Sam Song¹, Sota Oguro¹, Andras Lasso³, Fiona M. Fennessy¹, Yi Tang¹, Nobuhiko Hata¹, Clare M. Tempany¹

¹Radiology, Brigham & Women's Hospital, Boston, MA, USA; ²The Johns Hopkins University, Baltimore, MD, USA; ³School of Computing, Queens University, ON, Canada

Nine patients with clinically suspected prostate cancer underwent 3T MRI-guided transperineal targeted prostate biopsy successfully in the lithotomy position without significant compications using local anesthesia and intravenous procedural sedation. Multiparametric diagnostic MRI data were registered to intraprocedural T2 weighted turbo spin echo images to facilitate targeting of index lesions. Needle location was confirmed using real-time 2D FISP. Of eight biopsy results available, two were proved cancer and six showed no malignancy. We have shown this approach to be feasible and safe. It can yield clinically useful results in patients with index lesion on diagnostic MRI.