Mrcia
Silva de Oliveira1,2, Luiz Eduardo Betting, 23,
Fernando Cendes, 23, Gabriela Castellano1,2
1Neurophysics
Group, State University of Campinas (Unicamp), Campinas, SP, Brazil; 2CInAPCe
(Cooperao Interinstitucional de Apoio a Pesquisas sobre o Crebro), So Paulo
State, Brazil; 3NeuroImage Laboratory, State University of
Campinas (Unicamp), Campinas, SP, Brazil
Juvenile
myoclonic epilepsy (JME) is the most frequent subsyndrome of the idiopathic
generalized epilepsies. Experimental investigations support that the thalamus
is a key structure in the mechanisms of JME. The objective of this study was
to investigate the thalamus of patients with JME using texture analysis, a
quantitative neuroimaging technique. Patients and controls were submitted to
MRI investigation. The T1 volumetric sequence was used for thalamic
segmentation and extraction of texture parameters. Texture analysis revealed
differences between the thalamus of patients and controls. The present
investigation supports the participation of the thalamus in the mechanisms of
JME.