Robert Merwa1,
Karin Kapp2, Franz Ebner3, Thorsten Feiweier4,
Gernot Reishofer3, Rudolf Stollberger5
1Medical Engineering, FH O - Upper
Austria University of Applied Sciences, Linz, Austria; 2Department
of Radiation Therapy, Medical University of Graz, Graz, Austria; 3Department
of Radiology, Medical University of Graz, Graz, Austria; 4Healthcare,
Siemens AG, Germany; 5Institute of Medical Engineering, Graz
University of Technology, Graz, Austria
DCE
MRI was performed at 3 T in combination with a special sequence in order to
determine B1 inhomogenities. AIF and tissue concentrations were
calculated and the kinetic parameters Ktrans and Ve
were determined with a generalized kinetic model. The absolute deviation of
the maximum value of two comparable AIFs can be improved by a factor up to 70
and the root mean square deviation concerning the two AIFs can be decreased
by a factor up to 30 if B1 inhomogeneities are corrected. Also the
deviations of Ktrans and Ve in respect of the two AIFs are significantly
lower.