Trong-Kha Truong1, Nan-kuei Chen1,
Allen W. Song1
1Brain Imaging and Analysis Center,
Duke University, Durham, NC, United States
Diffusion
tensor imaging (DTI) is vulnerable to spatial and temporal B0 variations due to
susceptibility effects, eddy currents, subject motion, physiological noise,
and system instabilities, resulting in geometric distortions and subsequent
errors in the derivation of the diffusion tensor. Here, we propose a novel
method based on k-space energy spectrum analysis, which can inherently and
dynamically generate a B0
map from the k-space data for each baseline (b = 0) and diffusion-weighted image, without requiring any
additional data acquisition, to effectively and efficiently correct for such
artifacts and achieve a high spatial fidelity and accuracy.