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Abstract #4985

Correction for T1 Determined Using Rapid Look-Locker B-SSFP and a Simple Two Parameter Model Fit

Neville D. Gai1, John A. Butman1

1Radiology & Imaging Sciences, National Institutes of Health, Bethesda, MD, United States


A correction scheme for modulated longitudinal magnetization and incomplete inversion recovery Look-Locker sequence with balanced SSFP acquisition is described. Correction for such a scheme typically uses a three parameter model which requires acquisition of several (6 to 10) phases. It is shown that the two parameter inversion recovery model provides excellent fit over a wide range of TR/T1 and flip angle parameter space. The T1* obtained is easily corrected using a linear model. The correction was tested in phantoms and in head scans of several volunteers and shown to be accurate. Use of the two parameter model requires fewer acquisition phases (3 to 5) leading to improved temporal and spatial resolution.