Ziqi Sun1, Robert Bartha2
1The Ohio State University, Columbus,
OH, United States; 2Robarts Research Institute, London, Ontario,
Canada
A
spin-echo (SE) pulse sequence incorporated with two selective adiabatic full
passage (AFP) pulse trains separated by a time delay tau (varying with TE)
and located symmetrically on both sides of an amplitude modulated 180 degree
refocusing pulse. Apparent T2 and diffusion measurements on a phantom of
multi-medium and multi-compartment demonstrated that the customized SE
sequence generated T2-weighted contrast that is specifically sensitive to
restricted diffusion in the phantom media in comparison to those of the
conventional SE and CPMG pulse sequences.