Alexey A. Samsonov1, Julia V. Velikina2,
John O. Fleming3, Mark L. Schiebler1, Aaron S. Field1
1Department of Radiology, University of
Wisconsin, Madison, WI, United States; 2Department of Medical
Physics, University of Wisconsin, Madison, WI, United States; 3Department
of Neurology, University of Wisconsin, Madison, WI, United States
In
this work, we present a method to accelerate MS imaging in longitudinal
studies through acquisition of fully sampled images at the baseline scan and
accelerated undersampled data at follow-ups.
W investigated feasibility to accelerate serial scanning of MS
patients with 3D pulse sequences (T2 FLAIR and T1 weighted after Gd
administration). Our results indicate
that the proposed technique has a potential to produce high-quality images from
significantly accelerated reduced follow-up acquisition (up to 8 times) and
correctly depict T2 and Gd+ lesion load and anatomical content.