Daniel Jason Aaron Margolis1, Timothy
McClure1, Steven Raman1
1Department of Radiological Sciences,
David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
Diffusion-weighted
imaging (DWI) and dynamic contrast enhancement (DCE) can localize prostate
cancer in situ, but it is unclear if one is superior. DWI, Ktrans, Kep, Ve,
and T2WI are compared with surgical pathology in 23 patients using a unitless
variable, the conspicuity ratio, the difference of the values from the ROI of
the lesion and the contralateral side, divided by the average of these
values. Prostate cancer is more conspicuous on DWI ADC maps and on DCE than
on T2WI, and more conspicuous on DCE than on ADC, but Ktrans and Kep are not
significantly different in terms of conspicuity.