Galen Durant Reed1,2, Peder E. Larson1,
John Kurhanewicz1,2, Daniel B. Vigneron1,2
1Radiology and Biomedical Imaging,
University of California, San Francisco, San Francisco, CA, United States; 2Joint
Graduate Group in Bioengineering, UCB / UCSF, Berkeley, CA, United States
The
long acquisition times for the 3D phase encoding traditionally employed in
proton magnetic resonance spectroscopic imaging (MRSI) of the prostate can be
prohibitively long. A 3T MRSI sequence with a flyback echo-planar readout
recently developed and clinically implemented at UCSF shows greatly reduced
scan times. This time reduction allows for larger acquisition matrices and
longer repetition times to avoid metabolite saturation. Comparison with a
1.5T 3D phase-encoded sequence showed that the flyback sequence can achieve
comparable spatial resolution, improved spectral resolution, and
significantly improved SNR in a shorter scan time.