Giulio Gambarota1, R L. Janiczek1,
Robert V. Mulkern2, Rex D. Newbould1, Brandon Whitcher1
1GlaxoSmithKline Clinical Imaging
Center, London, United Kingdom; 2Radiology, Children's Hospital
Boston, Boston, United States
In
clinical MR examinations of the prostate, a multiparametric approach (T1- and
T2-weighted images, quantitative measurement of the apparent diffusion
coefficient (ADC) of water, dynamic contrast-enhanced MRI) is becoming
standard procedure. The Carr-Purcell-Meiboom-Gill
(CPMG) approach has recently been proposed for T2 mapping of the prostate at
1.5 T. No such studies have been performed at 3 T. Translating the CPMG
sequence to 3 T is not straightforward and involves compromises in clinical
implementation. Here we have shown high quality measurements of T2 may be
obtained over the entire prostate by careful design of the clinical
acquisition.