Mortality and Frequency of Nephrogenic Systemic Fibrosis

Giles Roditi¹, Tara Collidge², Peter Thomson², Jamie Traynor², Patrick Mark³, Scott Morris², Keith Simpson²

Nephrogenic systemic fibrosis (NSF) mortality was compared to a matched renal replacement therapy (RRT) population. Records searched with NSF and GBCA exposure identified and onset of RRT with survival to death or census. 1826 patients with RRT, 1812 with outcome data. Total 17 cases of NSF. Survival for GBCA exposed and NSF cohort measured by RRT onset or post scan survival not significantly different between these groups. Frequency of NSF cases over years studied follows the number of CE-MRA scans performed suggesting GBCA exposure causally implicated in development of NSF