Differentiation of Benign and Malignant Solid Components of Ovarian Masses by Diffusion-Weighted MR Imaging with ADC Measurement

Mayumi Takeuchi¹, Kenji Matsuzaki¹, Hiromu Nishitani¹

We evaluated surgically proven 52 ovarian tumors (36 malignant; 6 borderline malignant; 10 benign). All 42 malignant/borderline malignant tumors showed homogeneous or heterogeneous high intensity on DWI, whereas 3 of 10 benign tumors (3 thecomas) showed high intensity. The ADCs in 42 malignant/borderline malignant tumors and in 10 benign tumors were 1.02 +/- 0.19 and 1.38 +/- 0.30, respectively (p<0.001). Using a cut off ADC of 1.15 had a sensitivity of 76%, specificity of 80%. The ADCs in high intense 3 thecomas on DWI were relatively low (1.08 to 1.20), possibly due to their abundant cellular nature as functioning tumors.