Nabil Saouti1, Anton Vonk Noordegraaf1,
Michael Ingrisch2, J. Tim Marcus1
1VU University Medical Center,
Amsterdam, Netherlands; 2Ludwig-Maximilian University, Munich,
Germany
The
aim is to visualise the perfusion of the lungs by the pulmonary and bronchial
system separately, based on the fact that a contrast bolus injected
intravenously will arrive later in the bronchial than in the pulmonary
system. Included were 7 patients with whole left or right pulmonary artery
atresia, and 6 chronic thromboembolic pulmonary hypertension patients. Using
3D dynamic contrast-enhanced MRI with 1 s temporal resolution, a 5 s
signal-intensity onset delay was measured between open lung or lung region,
and obstructed lung (region), providing evidence for bronchial arterial
supply after a pulmonary artery obstruction.