Abstract #4601

3D Hyperpolarized 3He Imaging of Human Lung with Isotropic Spatial Resolution Using 3D-Cones

Jian-Xiong Wang¹, Alexei V. Ouriadov², Jeffrey A. Stainsby³, Grace E. Parraga², Giles Santyr^2,4

¹Applied Science Laboratory, GE HEALTHCARE, London, ON, Canada; ²Robarts Research Institute, The University of Western Ontario, London, ON, Canada; ³Applied Science Laboratory, GE HEALTHCARE, Toronto, ON, Canada; ⁴Dept. of Medical Biophysics, The University of Western Ontario, London, ON, Canada

A true 3D isotropic spatial resolution imaging method for Hyperpolarized He-3 human lung imaging using 3D-cones sequence is presented. The isotropic voxel size improves accuracy for co-registration, lung volume measurement and analysis for abnormalities in the lung.